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This presentation aims at contributing towards resolving some of the most burning issues of multiple sclerosis research. Of central importance is the pathogenic relevance of flow inversions pushing back into particular venous drainages of the brain or spinal canal. The author is wholeheartedly convinced that by demonstrating the impact of these venous flow-inversions and their cerebrospinal fluid displacements, directly in vivo and/or at post mortem, the relevant venous anomalies can better be understood and remedied. Any feedback on the part of the reader would be very highly appreciated, including critical commentaries which might help to clarify many of the issues surrounding multiple sclerosis.

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© Dr. F. Alfons Schelling, M.D.